IGFBP6

Across TCGA patient cohorts, IGFBP6 RNA expression is significantly associated with the protein abundance of many other proteins, with 20,772 significant associations in total. GBM shows the largest number of these associations.

The most reproducible IGFBP6-associated proteins across cancer lineages are LGALS1, EHD2, and ISLR. Each is linked with IGFBP6 in more than 7 cancer types. Because this analysis shows association rather than direction, both IGFBP6-to-partner and partner-to-IGFBP6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IGFBP6 versus LGALS1 in COAD, with a Pearson correlation of 0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IGFBP6→partner) and Y-score (partner→IGFBP6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	LGALS1 →	+0.764	+0.856	<.001	<.001	3	8
BRCA	EHD2 →	+0.721	+1.038	<.001	<.001	3	8
OV	ISLR →	+0.735	+1.081	<.001	<.001	3	8
GBM	LUM →	+1.090	+1.241	<.001	<.001	3	8
UCEC	MSRB3 →	+0.985	+1.405	<.001	<.001	3	8
UCEC	PDLIM4 →	+0.735	+1.459	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,772 associations by consensus.

IGFBP6 vs LGALS1 — COAD

Explore this scatter interactively →