IGFBP4

Across TCGA patient cohorts, IGFBP4 RNA expression is significantly associated with the protein abundance of many other proteins, with 19,398 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible IGFBP4-associated proteins across cancer lineages are KANK2, TNS1, and OLFML1. Each is linked with IGFBP4 in more than 8 cancer types. Because this analysis shows association rather than direction, both IGFBP4-to-partner and partner-to-IGFBP4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IGFBP4 versus KANK2 in COAD, with a Pearson correlation of 0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IGFBP4→partner) and Y-score (partner→IGFBP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	KANK2 →	+0.520	+0.688	<.001	<.001	3	9
OV	TNS1 →	+0.806	+1.719	<.001	<.001	3	8
UCEC	OLFML1 →	+0.768	+0.994	.002	.001	3	8
GBM	PCOLCE →	+0.829	+0.980	<.001	<.001	3	8
OV	CAVIN1 →	+0.681	+1.084	<.001	<.001	3	8
OV	CAVIN3 →	+0.765	+1.295	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,398 associations by consensus.

IGFBP4 vs KANK2 — COAD

Explore this scatter interactively →