IGFBP4

Across TCGA patient cohorts, IGFBP4 mutation is significantly associated with the RNA expression of many other genes, with 472 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible IGFBP4-associated genes across cancer lineages are RNU6-929P, FAUP2, and RN7SL654P. Each is linked with IGFBP4 in more than 1 cancer types. Because this analysis shows association rather than direction, both IGFBP4-to-partner and partner-to-IGFBP4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-929P grouped by IGFBP4-low versus IGFBP4-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IGFBP4→partner) and Y-score (partner→IGFBP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	RNU6-929P →	+0.297	+6.902	<.001	<.001	3	2
UCEC	FAUP2 →	+0.296	+2.194	.001	.009	3	2
UCEC	RN7SL654P →	+0.147	+3.109	<.001	.007	3	2
UCEC	RN7SL453P →	+0.079	+4.148	<.001	.006	3	2
COAD	RN7SKP47 →	+0.349	+5.003	.005	.004	3	2
COAD	RN7SL191P →	+0.538	+4.951	.003	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 472 associations by consensus.

RNU6-929P by IGFBP4 expression — LIHC

Explore this box plot interactively →