Across TCGA patient cohorts, IGF2R RNA expression is significantly associated with the protein abundance of many other proteins, with 8,278 significant associations in total. GBM shows the largest number of these associations.

The most reproducible IGF2R-associated proteins across cancer lineages are IGF2R_S2409, NUFIP2_S572, and MAP3K4. Each is linked with IGF2R in more than 3 cancer types. Because this analysis shows association rather than direction, both IGF2R-to-partner and partner-to-IGF2R results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IGF2R→partner) and Y-score (partner→IGF2R) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	IGF2R_S2409 →	+0.644	+0.482	<.001	<.001	3	4
LUAD	NUFIP2_S572 →	+0.430	+0.426	<.001	<.001	3	3
GBM	MAP3K4 →	+0.235	+0.335	<.001	<.001	3	3
BRCA	PDCD2 →	+0.280	+0.545	.002	<.001	3	3
GBM	PLIN2 →	+0.963	+0.506	.002	<.001	3	3
GBM	PLOD3 →	+0.416	+0.340	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,278 associations by consensus.

Exploration

IGF2R survival (RNA) · tumor vs normal (RNA) · all IGF2R data types