IGF2BP2

Across TCGA patient cohorts, IGF2BP2 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,114 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IGF2BP2-associated proteins across cancer lineages are HMGA2, HMGA2_S105, and SDF2. Each is linked with IGF2BP2 in more than 6 cancer types. Because this analysis shows association rather than direction, both IGF2BP2-to-partner and partner-to-IGF2BP2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IGF2BP2 versus HMGA2 in GBM, with a Pearson correlation of 0.56.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IGF2BP2→partner) and Y-score (partner→IGF2BP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	HMGA2 →	+1.341	+1.912	.001	<.001	3	7
GBM	HMGA2_S105 →	+1.624	+2.261	<.001	<.001	3	7
UCEC	SDF2 →	+0.484	+1.922	<.001	<.001	3	6
UCEC	MTHFD2 →	+0.629	+1.479	<.001	.002	3	6
LSCC	PES1 →	+0.327	+1.348	<.001	<.001	3	6
LUAD	HMGA1_S9 →	+1.245	+1.421	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,114 associations by consensus.

IGF2BP2 vs HMGA2 — GBM

Explore this scatter interactively →