IGF2BP2

Across TCGA cell cohorts, IGF2BP2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,221 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible IGF2BP2-associated GO terms across cancer lineages are Regulation of fibroblast proliferation, Regulation of cell-matrix adhesion, and Regulation of cell-substrate junction organization. Each is linked with IGF2BP2 in more than 11 cancer types. Because this analysis shows association rather than direction, both IGF2BP2-to-partner and partner-to-IGF2BP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of fibroblast proliferation grouped by IGF2BP2-low versus IGF2BP2-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IGF2BP2→partner) and Y-score (partner→IGF2BP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Regulation of fibroblast proliferation →	+0.111	+1.385	<.001	.002	3	12
BONE	Regulation of cell-matrix adhesion →	+0.140	+1.341	<.001	<.001	3	12
BONE	Regulation of cell-substrate junction organization →	+0.128	+1.666	.001	<.001	3	12
LIVER	Cellular response to prostaglandin stimulus →	-0.394	-1.063	<.001	<.001	3	11
BONE	Regulation of focal adhesion assembly →	+0.148	+1.403	<.001	<.001	3	11
KIDNEY	Chemokine (C-C motif) ligand 21 signaling pathway →	+0.169	+1.025	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,221 associations by consensus.

Regulation of fibroblast proliferation by IGF2BP2 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →