IGDCC4

Across TCGA patient cohorts, IGDCC4 RNA expression is significantly associated with the RNA expression of many other genes, with 19,102 significant associations in total. UVM shows the largest number of these associations.

The most reproducible IGDCC4-associated genes across cancer lineages are GLI3, CALU, and FBN1. Each is linked with IGDCC4 in more than 29 cancer types. Because this analysis shows association rather than direction, both IGDCC4-to-partner and partner-to-IGDCC4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IGDCC4 versus GLI3 in TGCT, with a Pearson correlation of 0.88.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IGDCC4→partner) and Y-score (partner→IGDCC4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
TGCT	GLI3 →	+1.790	+1.707	<.001	<.001	3	30
ACC	CALU →	+1.474	+1.733	<.001	<.001	3	30
HNSC	FBN1 →	+2.244	+0.906	<.001	<.001	3	30
DLBC	ANTXR1 →	+2.106	+1.098	<.001	<.001	3	30
UCS	TSHZ3 →	+2.037	+1.986	<.001	<.001	3	30
UCS	ARHGEF6 →	+1.275	+1.918	<.001	.001	2	30

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,102 associations by consensus.

IGDCC4 vs GLI3 — TGCT

Explore this scatter interactively →