IGDCC4

Across TCGA cell cohorts, IGDCC4 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,447 significant associations in total. STOMACH shows the largest number of these associations.

The most reproducible IGDCC4-associated GO terms across cancer lineages are Translational initiation, Cytoplasmic translation, and Cytoplasmic translational initiation. Each is linked with IGDCC4 in more than 12 cancer types. Because this analysis shows association rather than direction, both IGDCC4-to-partner and partner-to-IGDCC4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Translational initiation grouped by IGDCC4-low versus IGDCC4-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IGDCC4→partner) and Y-score (partner→IGDCC4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Translational initiation →	+0.071	+1.487	.002	.005	3	13
OESOPHAGUS	Cytoplasmic translation →	+0.120	+0.776	.001	.002	2	12
SOFT_TISSUE	Cytoplasmic translational initiation →	+0.063	+1.315	.005	.004	3	10
BLOOD_Lymphoma	Negative regulation of calcium ion export across plasma membrane →	+0.045	+0.277	.001	.004	3	10
STOMACH	Regulation of protein localization to Cajal body →	+0.087	+1.534	<.001	.003	3	10
STOMACH	Positive regulation of protein localization to Cajal body →	+0.087	+1.534	<.001	.003	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,447 associations by consensus.

Translational initiation by IGDCC4 expression — STOMACH

Explore this box plot interactively →