IGDCC3

Across TCGA patient cohorts, IGDCC3 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,574 significant associations in total. GBM shows the largest number of these associations.

The most reproducible IGDCC3-associated proteins across cancer lineages are MRPL41, TNKS1BP1_S1297, and OLFML3. Each is linked with IGDCC3 in more than 3 cancer types. Because this analysis shows association rather than direction, both IGDCC3-to-partner and partner-to-IGDCC3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IGDCC3 versus MRPL41 in OV, with a Pearson correlation of -0.25.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IGDCC3→partner) and Y-score (partner→IGDCC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	MRPL41 →	-0.285	-0.559	.009	.005	3	3
HNSC	TNKS1BP1_S1297 →	-0.429	-0.125	.001	.003	2	4
CCRCC	OLFML3 →	+0.812	+0.086	<.001	<.001	3	3
BRCA	SND1 →	-0.380	-0.771	<.001	.005	3	3
BRCA	ADI1 →	-0.446	-0.866	<.001	<.001	3	3
UCEC	CLUH →	-0.319	-0.429	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,574 associations by consensus.

IGDCC3 vs MRPL41 — OV

Explore this scatter interactively →