IGBP1P2

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, IGBP1P2 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated IGBP1P2 data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher IGBP1P2 RNA is associated with better overall survival. In most high-consensus cancer types, elevated IGBP1P2 expression acts as an unfavorable survival marker, although some lineages such as HNSC and CHOL show a favorable association.

HNSC, THYM, and CHOL are the cancer types where IGBP1P2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
HNSCOSQuartileIV0.5220.335.00558view →
THYMOSTertileAll0.8921.000.00337view →
CHOLOSTertileAll1.0000.498.02724view →
MESODFSTertileIV0.1630.379.02621view →
LUSCOSQuartileII,III,IV0.1890.463<.00121view →
KIRPDFSQuartileII,III,IV0.8580.594.02719view →
KIRCDFSQuartileII,III,IV0.7150.508.01718view →
STADOSQuartileII,III,IV0.5010.752.01912view →
READDFSTertileAll0.7070.889.02610view →
LUADDFSMedianIII,IV0.4170.210.01110view →
DLBCOSTertileAll0.6430.941.0479view →
THCADFSTertileII,III,IV0.2640.812.0239view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

IGBP1P2–HNSC (OS)

Kaplan–Meier survival curve for IGBP1P2 RNA-high vs -low samples in HNSC.

Open the HNSC breakdown →

Exploration