IGBP1

Across TCGA cell cohorts, IGBP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,454 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible IGBP1-associated GO terms across cancer lineages are Negative regulation of stress-activated MAPK cascade, Negative regulation of stress-activated protein kinase signaling cascade, and COPII vesicle coating. Each is linked with IGBP1 in more than 14 cancer types. Because this analysis shows association rather than direction, both IGBP1-to-partner and partner-to-IGBP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of stress-activated MAPK cascade grouped by IGBP1-low versus IGBP1-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IGBP1→partner) and Y-score (partner→IGBP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Negative regulation of stress-activated MAPK cascade →	+0.197	+0.975	<.001	<.001	3	15
BREAST	Negative regulation of stress-activated protein kinase signaling cascade →	+0.218	+0.902	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	COPII vesicle coating →	+0.100	+0.591	.004	.005	3	10
STOMACH	Positive regulation of nuclear cell cycle DNA replication →	-0.130	-0.598	<.001	.008	2	9
OESOPHAGUS	Positive regulation of cell cycle phase transition →	-0.103	-0.808	.005	.001	3	8
OESOPHAGUS	Positive regulation of mitotic cell cycle phase transition →	-0.115	-0.978	.003	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,454 associations by consensus.

Negative regulation of stress-activated MAPK cascade by IGBP1 expression — BREAST

Explore this box plot interactively →