IFTAP

Across TCGA patient cohorts, IFTAP protein abundance is significantly associated with the RNA expression of many other genes, with 612 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IFTAP-associated genes across cancer lineages are SYNGR1, CCDC113, and GIPR. Each is linked with IFTAP in more than 1 cancer types. Because this analysis shows association rather than direction, both IFTAP-to-partner and partner-to-IFTAP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IFTAP versus SYNGR1 in UCEC, with a Pearson correlation of 0.81.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IFTAP→partner) and Y-score (partner→IFTAP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SYNGR1 →	+2.562	+1.297	.005	.005	3	1
UCEC	CCDC113 →	+2.540	+1.242	.004	.009	3	1
UCEC	GIPR →	+1.560	+0.929	.005	.008	3	1
UCEC	CCDC114 →	+2.253	+1.032	.004	.008	3	1
UCEC	TUBD1 →	-0.301	-0.777	<.001	.003	3	1
UCEC	SLC6A7 →	-0.277	-1.240	.002	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 612 associations by consensus.

IFTAP vs SYNGR1 — UCEC

Explore this scatter interactively →