IFTAP

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, IFTAP mutation is significantly associated with the immune_cell of many other genes, with 1 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible IFTAP-associated genes across cancer lineages are Th2 cells. Each is linked with IFTAP in more than 1 cancer types. Because this analysis shows association rather than direction, both IFTAP-to-partner and partner-to-IFTAP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Th2 cells grouped by IFTAP-low versus IFTAP-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IFTAP→partner) and Y-score (partner→IFTAP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECTh2 cells →+0.269+3.008.004.01931
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

Th2 cells by IFTAP expression — UCEC

Box plot of Th2 cells in IFTAP-low vs IFTAP-high samples in UCEC.

Explore this box plot interactively →

Exploration