IFT88

Across TCGA patient cohorts, IFT88 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,346 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible IFT88-associated proteins across cancer lineages are IFT140, NAXD, and ZMYM2. Each is linked with IFT88 in more than 6 cancer types. Because this analysis shows association rather than direction, both IFT88-to-partner and partner-to-IFT88 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IFT88 versus IFT140 in BRCA, with a Pearson correlation of 0.60.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IFT88→partner) and Y-score (partner→IFT88) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	IFT140 →	+0.395	+0.725	<.001	<.001	3	7
OV	NAXD →	+0.480	+0.557	<.001	.001	3	7
LSCC	ZMYM2 →	+0.461	+0.689	<.001	<.001	3	6
COAD	SUGT1 →	+0.270	+0.427	<.001	<.001	3	6
BRCA	TTC21B →	+0.396	+0.785	<.001	<.001	3	6
OV	WDR19 →	+0.456	+0.694	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,346 associations by consensus.

IFT88 vs IFT140 — BRCA

Explore this scatter interactively →