IFT88

Across TCGA patient cohorts, IFT88 protein abundance is significantly associated with the RNA expression of many other genes, with 12,203 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible IFT88-associated genes across cancer lineages are TSNAXIP1, DNAH7, and CCDC173. Each is linked with IFT88 in more than 6 cancer types. Because this analysis shows association rather than direction, both IFT88-to-partner and partner-to-IFT88 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IFT88 versus TSNAXIP1 in UCEC, with a Pearson correlation of 0.64.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IFT88→partner) and Y-score (partner→IFT88) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TSNAXIP1 →	+1.177	+0.449	<.001	<.001	3	7
UCEC	DNAH7 →	+1.078	+0.448	<.001	<.001	3	7
UCEC	CCDC173 →	+0.821	+0.474	<.001	<.001	3	7
UCEC	LRGUK →	+0.760	+0.340	<.001	<.001	3	7
BRCA	DRC3 →	+1.217	+0.450	<.001	<.001	3	7
BRCA	IFT140 →	+1.173	+0.343	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,203 associations by consensus.

IFT88 vs TSNAXIP1 — UCEC

Explore this scatter interactively →