IFT81

Across TCGA patient cohorts, IFT81 protein abundance is significantly associated with the RNA expression of many other genes, with 5,315 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible IFT81-associated genes across cancer lineages are DNAI1, DNAH7, and LRRIQ1. Each is linked with IFT81 in more than 5 cancer types. Because this analysis shows association rather than direction, both IFT81-to-partner and partner-to-IFT81 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IFT81 versus DNAI1 in UCEC, with a Pearson correlation of 0.71.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IFT81→partner) and Y-score (partner→IFT81) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	DNAI1 →	+2.360	+0.538	<.001	<.001	3	6
UCEC	DNAH7 →	+1.091	+0.504	<.001	<.001	3	5
UCEC	LRRIQ1 →	+1.301	+0.437	<.001	<.001	3	5
UCEC	MDH1B →	+1.293	+0.421	<.001	<.001	3	5
GBM	CCDC40 →	+0.871	+0.387	<.001	<.001	3	5
OV	PIH1D2 →	+0.820	+0.638	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,315 associations by consensus.

IFT81 vs DNAI1 — UCEC

Explore this scatter interactively →