IFT81

Across TCGA patient cohorts, IFT81 mutation is significantly associated with the RNA expression of many other genes, with 805 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible IFT81-associated genes across cancer lineages are RN7SL571P, MIR3193, and MIR4445. Each is linked with IFT81 in more than 1 cancer types. Because this analysis shows association rather than direction, both IFT81-to-partner and partner-to-IFT81 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL571P grouped by IFT81-low versus IFT81-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IFT81→partner) and Y-score (partner→IFT81) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RN7SL571P →	+0.166	+5.455	<.001	.001	3	2
UCEC	MIR3193 →	+0.515	+1.838	<.001	.002	3	2
UCEC	MIR4445 →	+0.118	+3.834	<.001	.007	3	2
UCEC	CCL27 →	+0.019	+3.470	<.001	.002	3	2
CESC	LINC02061 →	+0.088	+4.812	<.001	.006	3	2
COAD	RPS29P32 →	+0.751	+6.251	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 805 associations by consensus.

RN7SL571P by IFT81 expression — BLCA

Explore this box plot interactively →