IFT81

Across TCGA cell cohorts, IFT81 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,454 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible IFT81-associated GO terms across cancer lineages are Protein localization to cilium, Intraciliary anterograde transport, and Microtubule-based transport. Each is linked with IFT81 in more than 19 cancer types. Because this analysis shows association rather than direction, both IFT81-to-partner and partner-to-IFT81 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein localization to cilium grouped by IFT81-low versus IFT81-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IFT81→partner) and Y-score (partner→IFT81) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Protein localization to cilium →	+0.069	+1.164	<.001	<.001	3	20
STOMACH	Intraciliary anterograde transport →	+0.110	+1.025	<.001	.002	3	18
LUNG_SCLC	Microtubule-based transport →	+0.072	+1.196	<.001	<.001	3	18
STOMACH	Transport along microtubule →	+0.058	+0.787	<.001	.003	3	18
BREAST	Cytoskeleton-dependent intracellular transport →	+0.054	+1.222	<.001	<.001	3	18
PANCREAS	Intraciliary transport involved in cilium assembly →	+0.145	+0.883	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,454 associations by consensus.

Protein localization to cilium by IFT81 expression — OVARY

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