IFT52

Across TCGA cell cohorts, IFT52 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,230 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible IFT52-associated GO terms across cancer lineages are Protein localization to cilium, Protein localization to ciliary transition zone, and Protein localization to non-motile cilium. Each is linked with IFT52 in more than 14 cancer types. Because this analysis shows association rather than direction, both IFT52-to-partner and partner-to-IFT52 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein localization to cilium grouped by IFT52-low versus IFT52-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IFT52→partner) and Y-score (partner→IFT52) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Protein localization to cilium →	+0.077	+0.963	<.001	.001	2	15
LIVER	Protein localization to ciliary transition zone →	+0.107	+0.651	<.001	.001	3	14
OESOPHAGUS	Protein localization to non-motile cilium →	+0.106	+0.897	.004	.007	3	14
URINARY_TRACT	Positive regulation of organelle assembly →	+0.066	+1.056	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Transcription initiation at RNA polymerase II promoter →	+0.063	+0.797	<.001	.007	3	12
LIVER	Regulation of cilium assembly →	+0.061	+0.651	.002	.003	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,230 associations by consensus.

Protein localization to cilium by IFT52 expression — OESOPHAGUS

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