IFT46

Across TCGA patient cohorts, IFT46 protein abundance is significantly associated with the RNA expression of many other genes, with 11,008 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible IFT46-associated genes across cancer lineages are IQUB, SPEF1, and LRRC23. Each is linked with IFT46 in more than 6 cancer types. Because this analysis shows association rather than direction, both IFT46-to-partner and partner-to-IFT46 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IFT46 versus IQUB in UCEC, with a Pearson correlation of 0.62.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IFT46→partner) and Y-score (partner→IFT46) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	IQUB →	+1.181	+0.422	<.001	<.001	3	7
UCEC	SPEF1 →	+1.620	+0.315	<.001	<.001	3	7
UCEC	LRRC23 →	+1.490	+0.401	<.001	<.001	3	7
UCEC	DNAI1 →	+2.018	+0.426	<.001	<.001	3	7
OV	IQCK →	+0.746	+0.641	.001	<.001	3	7
BRCA	CFAP91 →	+0.874	+0.442	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,008 associations by consensus.

IFT46 vs IQUB — UCEC

Explore this scatter interactively →