IFT46

Across TCGA cell cohorts, IFT46 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,938 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible IFT46-associated GO terms across cancer lineages are Negative regulation of mitotic cell cycle phase transition, Spliceosomal tri-snRNP complex assembly, and Ether catabolic process. Each is linked with IFT46 in more than 8 cancer types. Because this analysis shows association rather than direction, both IFT46-to-partner and partner-to-IFT46 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of mitotic cell cycle phase transition grouped by IFT46-low versus IFT46-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IFT46→partner) and Y-score (partner→IFT46) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Negative regulation of mitotic cell cycle phase transition →	+0.050	+0.853	<.001	<.001	3	9
UPPER_AERODIGESTIVE_TRACT	Spliceosomal tri-snRNP complex assembly →	+0.096	+0.970	.004	<.001	3	9
OESOPHAGUS	Ether catabolic process →	+0.280	+1.478	<.001	.001	3	8
OESOPHAGUS	Glycerol ether catabolic process →	+0.280	+1.478	<.001	.001	3	8
OESOPHAGUS	Platelet activating factor catabolic process →	+0.280	+1.478	<.001	.001	3	8
SOFT_TISSUE	Protein-DNA complex assembly →	+0.063	+1.111	<.001	.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,938 associations by consensus.

Negative regulation of mitotic cell cycle phase transition by IFT46 expression — OVARY

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