IFT43

Across TCGA cell cohorts, IFT43 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,214 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible IFT43-associated GO terms across cancer lineages are Oxidative RNA demethylation, Protein catabolic process at synapse, and Protein catabolic process at postsynapse. Each is linked with IFT43 in more than 11 cancer types. Because this analysis shows association rather than direction, both IFT43-to-partner and partner-to-IFT43 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Oxidative RNA demethylation grouped by IFT43-low versus IFT43-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IFT43→partner) and Y-score (partner→IFT43) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Oxidative RNA demethylation →	+0.109	+0.722	.006	.008	3	12
BLOOD_Lymphoma	Protein catabolic process at synapse →	+0.147	+1.095	<.001	<.001	3	12
BLOOD_Lymphoma	Protein catabolic process at postsynapse →	+0.147	+1.095	<.001	<.001	3	12
BREAST	Protein localization to ciliary transition zone →	+0.076	+0.768	.004	<.001	2	12
BONE	Vesicle targeting, rough ER to cis-Golgi →	+0.123	+0.962	<.001	<.001	3	11
LUNG_NSCLC_LUAD	Protein localization to cilium →	+0.059	+0.655	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,214 associations by consensus.

Oxidative RNA demethylation by IFT43 expression — STOMACH

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