IFT27

Across TCGA patient cohorts, IFT27 protein abundance is significantly associated with the RNA expression of many other genes, with 19,297 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible IFT27-associated genes across cancer lineages are DNAL4, CBY1, and LRRC23. Each is linked with IFT27 in more than 5 cancer types. Because this analysis shows association rather than direction, both IFT27-to-partner and partner-to-IFT27 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IFT27 versus DNAL4 in UCEC, with a Pearson correlation of 0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IFT27→partner) and Y-score (partner→IFT27) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	DNAL4 →	+0.706	+0.359	<.001	<.001	3	6
HNSC	CBY1 →	+0.515	+0.295	<.001	.006	3	5
UCEC	LRRC23 →	+1.727	+0.541	<.001	<.001	3	5
UCEC	MDH1B →	+1.619	+0.494	<.001	<.001	3	5
BRCA	CCDC74B →	+1.021	+0.369	<.001	<.001	3	5
HNSC	TTLL1 →	+0.567	+0.315	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,297 associations by consensus.

IFT27 vs DNAL4 — UCEC

Explore this scatter interactively →