IFT27

Across TCGA cell cohorts, IFT27 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,233 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible IFT27-associated GO terms across cancer lineages are Macroautophagy, Sperm motility, and Flagellated sperm motility. Each is linked with IFT27 in more than 10 cancer types. Because this analysis shows association rather than direction, both IFT27-to-partner and partner-to-IFT27 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Macroautophagy grouped by IFT27-low versus IFT27-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IFT27→partner) and Y-score (partner→IFT27) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Macroautophagy →	+0.082	+1.750	<.001	<.001	3	11
SOFT_TISSUE	Sperm motility →	-0.087	-1.923	<.001	<.001	3	11
SOFT_TISSUE	Flagellated sperm motility →	-0.087	-1.923	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Autophagy →	+0.081	+1.505	<.001	<.001	3	10
SKIN	Intraciliary retrograde transport →	+0.049	+0.910	<.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Process utilizing autophagic mechanism →	+0.081	+1.505	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,233 associations by consensus.

Macroautophagy by IFT27 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →