IFT20

Across TCGA patient cohorts, IFT20 protein abundance is significantly associated with the RNA expression of many other genes, with 17,906 significant associations in total. GBM shows the largest number of these associations.

The most reproducible IFT20-associated genes across cancer lineages are LRRC23, LRRC43, and PIH1D2. Each is linked with IFT20 in more than 4 cancer types. Because this analysis shows association rather than direction, both IFT20-to-partner and partner-to-IFT20 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IFT20 versus LRRC23 in UCEC, with a Pearson correlation of 0.53.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IFT20→partner) and Y-score (partner→IFT20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	LRRC23 →	+1.514	+0.549	<.001	<.001	3	5
UCEC	LRRC43 →	+0.890	+0.357	<.001	<.001	3	4
BRCA	PIH1D2 →	+0.801	+0.421	<.001	<.001	3	4
UCEC	C17orf97 →	+0.762	+0.422	<.001	<.001	3	4
UCEC	LINC02166 →	+0.950	+0.297	<.001	<.001	3	4
BRCA	SAMD15 →	+1.200	+0.406	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,906 associations by consensus.

IFT20 vs LRRC23 — UCEC

Explore this scatter interactively →