IFT172

Across TCGA patient cohorts, IFT172 protein abundance is significantly associated with the RNA expression of many other genes, with 11,837 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible IFT172-associated genes across cancer lineages are CCDC113, LRRC23, and NEK11. Each is linked with IFT172 in more than 4 cancer types. Because this analysis shows association rather than direction, both IFT172-to-partner and partner-to-IFT172 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IFT172 versus CCDC113 in UCEC, with a Pearson correlation of 0.71.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IFT172→partner) and Y-score (partner→IFT172) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CCDC113 →	+1.355	+0.414	<.001	<.001	3	5
UCEC	LRRC23 →	+1.666	+0.427	<.001	<.001	3	5
BRCA	NEK11 →	+1.101	+0.344	<.001	<.001	3	5
UCEC	C20orf85 →	+3.332	+0.415	<.001	<.001	3	5
UCEC	MDH1B →	+1.280	+0.396	<.001	<.001	3	5
BRCA	PIH1D2 →	+0.957	+0.369	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,837 associations by consensus.

IFT172 vs CCDC113 — UCEC

Explore this scatter interactively →