IFT172

Across TCGA cell cohorts, IFT172 mutation is significantly associated with the RNA expression of many other genes, with 1,582 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible IFT172-associated genes across cancer lineages are GPRIN2, CCDC134, and PHF5A. Each is linked with IFT172 in more than 2 cancer types. Because this analysis shows association rather than direction, both IFT172-to-partner and partner-to-IFT172 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GPRIN2 grouped by IFT172-low versus IFT172-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IFT172→partner) and Y-score (partner→IFT172) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	GPRIN2 →	+0.024	+4.267	.002	<.001	3	3
LARGE_INTESTINE	CCDC134 →	+0.619	+3.321	.003	.002	3	2
LARGE_INTESTINE	PHF5A →	+0.398	+3.321	.009	.003	3	2
LARGE_INTESTINE	LONP2 →	+0.524	+3.169	.003	.009	3	2
LARGE_INTESTINE	MAST1 →	+0.653	+1.850	.006	.006	3	2
LARGE_INTESTINE	TTC33 →	+0.591	+2.364	.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,582 associations by consensus.

GPRIN2 by IFT172 expression — BLOOD_Leukemia

Explore this box plot interactively →