Across TCGA pan-cancer cohorts, IFT140 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated IFT140 data layer compared with 23 for mass-spec protein and 10 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher IFT140 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated IFT140 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and PDAC show a favorable association.

CCRCC, PDAC, and LUAD are the cancer types where IFT140 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Median	II,III,IV	0.887	0.283	.012	15	view →
PDAC	OS	Median	IV	0.937	0.395	.026	3	view →
LUAD	DFS	Median	All	0.716	0.515	.034	2	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: IFT140 tumor-vs-normal RNA expression · all IFT140 data types