Across TCGA patient cohorts, IFRD2 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,953 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IFRD2-associated proteins across cancer lineages are MCM4_S131, SETD2, and URB2. Each is linked with IFRD2 in more than 4 cancer types. Because this analysis shows association rather than direction, both IFRD2-to-partner and partner-to-IFRD2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IFRD2→partner) and Y-score (partner→IFRD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MCM4_S131 →	+0.885	+0.625	<.001	.006	3	5
OV	SETD2 →	+0.229	+0.484	.001	<.001	3	5
OV	URB2 →	+0.328	+0.454	<.001	<.001	3	4
GBM	POLR3C →	+0.309	+0.348	<.001	<.001	3	4
LSCC	DCP1A →	+0.239	+0.650	<.001	<.001	3	4
LSCC	GEMIN5 →	+0.226	+0.427	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,953 associations by consensus.

Exploration

IFRD2 survival (RNA) · tumor vs normal (RNA) · all IFRD2 data types