IFNW1

Across TCGA patient cohorts, IFNW1 mutation is significantly associated with the RNA expression of many other genes, with 1,117 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible IFNW1-associated genes across cancer lineages are LINC02719, PIN1, and MIR1273H. Each is linked with IFNW1 in more than 1 cancer types. Because this analysis shows association rather than direction, both IFNW1-to-partner and partner-to-IFNW1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC02719 grouped by IFNW1-low versus IFNW1-high in GBM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IFNW1→partner) and Y-score (partner→IFNW1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	LINC02719 →	+0.171	+5.352	<.001	.005	3	2
SKCM	PIN1 →	+0.482	+3.341	<.001	.005	3	2
UCEC	MIR1273H →	+0.230	+3.036	<.001	.009	3	2
SKCM	RAD54L →	+0.622	+2.719	.009	.003	3	2
SKCM	UBE2F-SCLY →	+0.069	+2.962	<.001	.001	3	2
SKCM	LINC02210-CRHR1 →	+0.061	+2.253	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,117 associations by consensus.

LINC02719 by IFNW1 expression — GBM

Explore this box plot interactively →