Across TCGA patient cohorts, IFNLR1 mutation is significantly associated with the RNA expression of many other genes, with 1,937 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible IFNLR1-associated genes across cancer lineages are RNU1-17P, SUPV3L1, and IQCC. Each is linked with IFNLR1 in more than 1 cancer types. Because this analysis shows association rather than direction, both IFNLR1-to-partner and partner-to-IFNLR1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IFNLR1→partner) and Y-score (partner→IFNLR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RNU1-17P →	+0.344	+7.734	<.001	<.001	3	2
UCEC	SUPV3L1 →	+0.392	+2.595	.003	<.001	3	2
UCEC	IQCC →	+0.558	+2.584	<.001	.001	3	2
UCEC	CDC25A →	+0.571	+2.168	.007	.009	3	2
UCEC	REEP4 →	+0.521	+2.617	.001	.005	3	2
UCEC	SHCBP1 →	+0.663	+2.595	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,937 associations by consensus.

Exploration

IFNLR1 survival (RNA) · tumor vs normal (RNA) · all IFNLR1 data types