Across TCGA cell cohorts, IFNLR1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,848 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible IFNLR1-associated GO terms across cancer lineages are Regulation of protein localization to nucleus, Type III interferon-mediated signaling pathway, and Cellular response to type III interferon. Each is linked with IFNLR1 in more than 12 cancer types. Because this analysis shows association rather than direction, both IFNLR1-to-partner and partner-to-IFNLR1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IFNLR1→partner) and Y-score (partner→IFNLR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Regulation of protein localization to nucleus →	+0.089	+1.161	<.001	<.001	3	13
BONE	Type III interferon-mediated signaling pathway →	-0.258	-0.961	<.001	<.001	3	12
BONE	Cellular response to type III interferon →	-0.258	-0.961	<.001	<.001	3	12
OVARY	Negative regulation of syncytium formation by plasma membrane fusion →	+0.102	+1.161	<.001	<.001	3	11
OVARY	Negative regulation of myoblast fusion →	+0.113	+1.393	<.001	<.001	3	11
BONE	Negative regulation of RNA splicing →	+0.132	+1.475	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,848 associations by consensus.

Exploration

IFNLR1 survival (RNA) · tumor vs normal (RNA) · all IFNLR1 data types