Across TCGA cell cohorts, IFNLR1 mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible IFNLR1-associated genes across cancer lineages are ARGFX, CENPVL1, and LACRT. Each is linked with IFNLR1 in more than 1 cancer types. Because this analysis shows association rather than direction, both IFNLR1-to-partner and partner-to-IFNLR1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IFNLR1→partner) and Y-score (partner→IFNLR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	ARGFX →	+0.010	+4.022	<.001	.006	3	1
LARGE_INTESTINE	CENPVL1 →	+0.150	+3.510	<.001	.003	3	1
OVARY	LACRT →	+0.038	+4.222	<.001	.006	3	1
OVARY	KRT82 →	+0.009	+3.700	<.001	.005	3	1
OVARY	TRIM64B →	+0.079	+3.938	.006	.005	3	1
LUNG_NSCLC_LUAD	GSX1 →	+0.122	+4.887	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

Exploration

IFNLR1 survival (RNA) · tumor vs normal (RNA) · all IFNLR1 data types