IFNL3P1

Across TCGA patient cohorts, IFNL3P1 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,069 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible IFNL3P1-associated GO terms across cancer lineages are Viral genome replication, Regulation of viral genome replication, and Heterochromatin organization. Each is linked with IFNL3P1 in more than 21 cancer types. Because this analysis shows association rather than direction, both IFNL3P1-to-partner and partner-to-IFNL3P1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Viral genome replication grouped by IFNL3P1-low versus IFNL3P1-high in UCS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IFNL3P1→partner) and Y-score (partner→IFNL3P1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCS	Viral genome replication →	+0.050	+0.730	<.001	<.001	3	22
UCS	Regulation of viral genome replication →	+0.060	+0.694	<.001	<.001	3	21
THYM	Heterochromatin organization →	+0.055	+0.506	<.001	<.001	3	20
ESCA	Interferon-mediated signaling pathway →	+0.054	+0.531	.001	<.001	1	22
UCS	Response to type I interferon →	+0.061	+0.565	<.001	.007	1	22
STAD	Regulation of defense response to virus →	+0.035	+0.406	<.001	<.001	3	20

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,069 associations by consensus.

Viral genome replication by IFNL3P1 expression — UCS

Explore this box plot interactively →