Across TCGA patient cohorts, IFNL2 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,653 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible IFNL2-associated GO terms across cancer lineages are Regulation of viral genome replication, Regulation of ribonuclease activity, and Interleukin-27-mediated signaling pathway. Each is linked with IFNL2 in more than 20 cancer types. Because this analysis shows association rather than direction, both IFNL2-to-partner and partner-to-IFNL2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IFNL2→partner) and Y-score (partner→IFNL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of viral genome replication →	+0.064	+0.324	<.001	<.001	3	21
THYM	Regulation of ribonuclease activity →	+0.114	+0.166	<.001	.006	3	20
MESO	Interleukin-27-mediated signaling pathway →	+0.115	+0.291	<.001	<.001	3	20
OV	MDA-5 signaling pathway →	+0.076	+0.249	<.001	<.001	3	19
STAD	Negative regulation of viral genome replication →	+0.076	+0.449	<.001	<.001	3	19
ESCA	Negative regulation of viral process →	+0.075	+0.321	<.001	<.001	3	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,653 associations by consensus.

Exploration

IFNL2 survival (RNA) · tumor vs normal (RNA) · all IFNL2 data types