Across TCGA patient cohorts, IFNL2 mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. LUSC shows the largest number of these associations.

The most reproducible IFNL2-associated genes across cancer lineages are CMP, Eosinophils, and Adipocytes. Each is linked with IFNL2 in more than 1 cancer types. Because this analysis shows association rather than direction, both IFNL2-to-partner and partner-to-IFNL2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IFNL2→partner) and Y-score (partner→IFNL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	CMP →	+0.024	+3.315	.011	.040	3	1
LUSC	Eosinophils →	+0.041	+3.173	.004	.049	3	1
UCEC	Adipocytes →	+0.024	+3.096	.020	.017	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Exploration

IFNL2 survival (RNA) · tumor vs normal (RNA) · all IFNL2 data types