Across TCGA cell cohorts, IFNL2 RNA expression is significantly associated with the go_rna of many other GO terms, with 652 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible IFNL2-associated GO terms across cancer lineages are Negative regulation of innate immune response, Negative regulation of viral process, and Acute-phase response. Each is linked with IFNL2 in more than 6 cancer types. Because this analysis shows association rather than direction, both IFNL2-to-partner and partner-to-IFNL2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IFNL2→partner) and Y-score (partner→IFNL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Negative regulation of innate immune response →	+0.117	+0.259	<.001	<.001	3	7
UPPER_AERODIGESTIVE_TRACT	Negative regulation of viral process →	+0.134	+0.189	<.001	<.001	3	6
UPPER_AERODIGESTIVE_TRACT	Acute-phase response →	+0.160	+0.200	.006	.003	2	7
UPPER_AERODIGESTIVE_TRACT	Regulation of viral life cycle →	+0.108	+0.182	<.001	<.001	3	6
OVARY	Positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity →	+0.153	+0.027	<.001	.001	3	6
BREAST	Negative regulation of response to biotic stimulus →	+0.094	+0.169	<.001	.007	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 652 associations by consensus.

Exploration

IFNL2 survival (RNA) · tumor vs normal (RNA) · all IFNL2 data types