IFNGR2

Across TCGA patient cohorts, IFNGR2 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,922 significant associations in total. GBM shows the largest number of these associations.

The most reproducible IFNGR2-associated proteins across cancer lineages are SERPINB1, PARP4, and ASPSCR1. Each is linked with IFNGR2 in more than 4 cancer types. Because this analysis shows association rather than direction, both IFNGR2-to-partner and partner-to-IFNGR2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IFNGR2 versus SERPINB1 in GBM, with a Pearson correlation of 0.65.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IFNGR2→partner) and Y-score (partner→IFNGR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SERPINB1 →	+0.568	+0.451	<.001	<.001	3	5
GBM	PARP4 →	+0.506	+0.429	<.001	<.001	3	5
BRCA	ASPSCR1 →	-0.231	-0.379	.002	.009	3	5
GBM	UGP2 →	+0.439	+0.498	<.001	<.001	3	4
GBM	S100A11 →	+0.854	+0.520	<.001	<.001	3	4
GBM	SH3GLB1 →	+0.391	+0.519	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,922 associations by consensus.

IFNGR2 vs SERPINB1 — GBM

Explore this scatter interactively →