IFNGR2

Across TCGA patient cohorts, IFNGR2 protein abundance is significantly associated with the RNA expression of many other genes, with 261 significant associations in total. GBM shows the largest number of these associations.

The most reproducible IFNGR2-associated genes across cancer lineages are SLC16A8, CHADL, and MANBAL. Each is linked with IFNGR2 in more than 1 cancer types. Because this analysis shows association rather than direction, both IFNGR2-to-partner and partner-to-IFNGR2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IFNGR2 versus SLC16A8 in GBM, with a Pearson correlation of 0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IFNGR2→partner) and Y-score (partner→IFNGR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SLC16A8 →	+0.703	+0.325	.007	.002	3	1
GBM	CHADL →	+1.476	+0.385	.001	.003	3	1
GBM	MANBAL →	-0.445	-0.408	.001	.001	3	1
GBM	LONP2 →	-0.373	-0.380	<.001	.003	3	1
GBM	KNOP1 →	-0.587	-0.471	.009	.008	3	1
GBM	CORO2B →	-0.855	-0.389	.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 261 associations by consensus.

IFNGR2 vs SLC16A8 — GBM

Explore this scatter interactively →