IFNG

Across TCGA cell cohorts, IFNG RNA expression is significantly associated with the go_rna of many other GO terms, with 462 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible IFNG-associated GO terms across cancer lineages are Detection of external biotic stimulus, Long-term memory, and Positive regulation of endothelial cell proliferation. Each is linked with IFNG in more than 2 cancer types. Because this analysis shows association rather than direction, both IFNG-to-partner and partner-to-IFNG results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Detection of external biotic stimulus grouped by IFNG-low versus IFNG-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IFNG→partner) and Y-score (partner→IFNG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Detection of external biotic stimulus →	+0.151	+0.785	<.001	.004	3	3
BLOOD_Myeloma	Long-term memory →	-0.113	-0.169	<.001	.001	3	2
SOFT_TISSUE	Positive regulation of endothelial cell proliferation →	-0.075	-0.033	<.001	.008	3	2
LUNG_SCLC	Cellular response to biotic stimulus →	-0.042	-0.087	.001	.002	3	2
LUNG_SCLC	Cellular response to molecule of bacterial origin →	-0.050	-0.086	.002	.002	3	2
LUNG_SCLC	Cellular response to lipopolysaccharide →	-0.056	-0.058	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 462 associations by consensus.

Detection of external biotic stimulus by IFNG expression — BLOOD_Lymphoma

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