IFNAR2

Across TCGA patient cohorts, IFNAR2 protein abundance is significantly associated with the RNA expression of many other genes, with 175 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IFNAR2-associated genes across cancer lineages are RPS6KA5, CRISPLD2, and PIP5K1B. Each is linked with IFNAR2 in more than 1 cancer types. Because this analysis shows association rather than direction, both IFNAR2-to-partner and partner-to-IFNAR2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IFNAR2 versus RPS6KA5 in LSCC, with a Pearson correlation of 0.57.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IFNAR2→partner) and Y-score (partner→IFNAR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	RPS6KA5 →	+0.655	+0.701	.001	.007	3	1
LSCC	CRISPLD2 →	+0.918	+0.701	<.001	.007	3	1
LSCC	PIP5K1B →	+0.835	+0.701	.005	.007	3	1
LSCC	FYN →	+0.668	+0.701	.002	.007	3	1
LSCC	TAS2R8 →	+0.243	+0.876	<.001	.007	3	1
LSCC	WWP1 →	+0.609	+0.702	.002	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 175 associations by consensus.

IFNAR2 vs RPS6KA5 — LSCC

Explore this scatter interactively →