IFNAR1

Across TCGA patient cohorts, IFNAR1 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,374 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible IFNAR1-associated proteins across cancer lineages are YARS2, ESF1, and MRPS30. Each is linked with IFNAR1 in more than 4 cancer types. Because this analysis shows association rather than direction, both IFNAR1-to-partner and partner-to-IFNAR1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IFNAR1 versus YARS2 in BRCA, with a Pearson correlation of -0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IFNAR1→partner) and Y-score (partner→IFNAR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	YARS2 →	-0.388	-0.437	<.001	<.001	3	5
LUAD	ESF1 →	-0.359	-0.354	<.001	<.001	3	4
COAD	MRPS30 →	-0.338	-0.415	<.001	<.001	3	4
BRCA	PTCD3 →	-0.352	-0.526	<.001	<.001	3	4
BRCA	WDR43 →	-0.326	-0.476	<.001	<.001	3	4
LUAD	RCOR2_S63 →	-1.499	-0.515	.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,374 associations by consensus.

IFNAR1 vs YARS2 — BRCA

Explore this scatter interactively →