IFNAR1

Across TCGA cell cohorts, IFNAR1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,011 significant associations in total. CNS shows the largest number of these associations.

The most reproducible IFNAR1-associated GO terms across cancer lineages are Positive regulation of cellular respiration, Cellular response to interferon-beta, and Retrograde transport, endosome to Golgi. Each is linked with IFNAR1 in more than 14 cancer types. Because this analysis shows association rather than direction, both IFNAR1-to-partner and partner-to-IFNAR1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of cellular respiration grouped by IFNAR1-low versus IFNAR1-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IFNAR1→partner) and Y-score (partner→IFNAR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Positive regulation of cellular respiration →	+0.137	+0.571	.001	.001	3	15
LUNG_SCLC	Cellular response to interferon-beta →	+0.158	+0.806	<.001	<.001	3	14
BLOOD_Lymphoma	Retrograde transport, endosome to Golgi →	+0.055	+1.101	<.001	<.001	3	14
SOFT_TISSUE	Endosomal transport →	+0.056	+0.796	<.001	<.001	3	13
OVARY	Cytosolic transport →	+0.065	+0.811	<.001	<.001	3	13
LUNG_SCLC	Interleukin-10-mediated signaling pathway →	+0.266	+0.557	<.001	.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,011 associations by consensus.

Positive regulation of cellular respiration by IFNAR1 expression — LUNG_SCLC

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