IFNA6

Across TCGA patient cohorts, IFNA6 mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible IFNA6-associated genes across cancer lineages are Tregs and CD4+ Tcm. Each is linked with IFNA6 in more than 1 cancer types. Because this analysis shows association rather than direction, both IFNA6-to-partner and partner-to-IFNA6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Tregs grouped by IFNA6-low versus IFNA6-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IFNA6→partner) and Y-score (partner→IFNA6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	Tregs →	+0.028	+2.979	<.001	.044	3	1
LUSC	CD4+ Tcm →	+0.009	+5.593	.004	.030	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Tregs by IFNA6 expression — SKCM

Explore this box plot interactively →