IFNA6

Across TCGA cell cohorts, IFNA6 RNA expression is significantly associated with the mutation status of many other genes, with 97 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible IFNA6-associated genes across cancer lineages are KIAA2026, FLG, and RICTOR. Each is linked with IFNA6 in more than 1 cancer types. Because this analysis shows association rather than direction, both IFNA6-to-partner and partner-to-IFNA6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KIAA2026 grouped by IFNA6-low versus IFNA6-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IFNA6→partner) and Y-score (partner→IFNA6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	KIAA2026 →	+3.321	+0.082	.002	.008	3	2
BLOOD_Leukemia	FLG →	+1.890	+0.084	.008	.001	3	2
BREAST	RICTOR →	+4.196	+0.072	.006	<.001	3	2
SOFT_TISSUE	TRPM6 →	+4.977	+0.022	.002	<.001	3	1
SOFT_TISSUE	IRF4 →	+5.977	+0.030	.001	<.001	3	1
SOFT_TISSUE	ADAMTS9 →	+4.977	+0.022	.002	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 97 associations by consensus.

KIAA2026 by IFNA6 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →