IFNA5

Across TCGA patient cohorts, IFNA5 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,161 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible IFNA5-associated GO terms across cancer lineages are Regulation of mRNA splicing, via spliceosome, Regulation of RNA splicing, and Respiratory chain complex IV assembly. Each is linked with IFNA5 in more than 14 cancer types. Because this analysis shows association rather than direction, both IFNA5-to-partner and partner-to-IFNA5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of mRNA splicing, via spliceosome grouped by IFNA5-low versus IFNA5-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IFNA5→partner) and Y-score (partner→IFNA5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of mRNA splicing, via spliceosome →	+0.056	+0.030	<.001	.001	3	15
STAD	Regulation of RNA splicing →	+0.056	+0.041	<.001	<.001	3	14
ESCA	Respiratory chain complex IV assembly →	+0.055	+0.073	<.001	<.001	3	14
STAD	Response to UV-C →	+0.043	+0.027	<.001	.003	3	14
STAD	Positive regulation of organelle assembly →	+0.054	+0.031	<.001	<.001	3	14
STAD	Cellular response to UV →	+0.052	+0.048	<.001	.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,161 associations by consensus.

Regulation of mRNA splicing, via spliceosome by IFNA5 expression — STAD

Explore this box plot interactively →