IFNA5

Across TCGA patient cohorts, IFNA5 mutation is significantly associated with the RNA expression of many other genes, with 145 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible IFNA5-associated genes across cancer lineages are EIF4EBP2P3, RPS12P24, and KRT18P66. Each is linked with IFNA5 in more than 2 cancer types. Because this analysis shows association rather than direction, both IFNA5-to-partner and partner-to-IFNA5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, EIF4EBP2P3 grouped by IFNA5-low versus IFNA5-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IFNA5→partner) and Y-score (partner→IFNA5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	EIF4EBP2P3 →	+0.053	+4.302	<.001	.007	3	3
UCEC	RPS12P24 →	+0.220	+3.454	<.001	<.001	3	2
UCEC	KRT18P66 →	+0.099	+2.329	<.001	.008	3	2
COAD	POLR3KP2 →	+0.255	+4.418	<.001	.008	3	2
LUAD	IGLVI-38 →	+0.194	+4.319	.001	.007	3	2
SKCM	RNU6-940P →	+0.192	+5.488	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 145 associations by consensus.

EIF4EBP2P3 by IFNA5 expression — SKCM

Explore this box plot interactively →