Across TCGA pan-cancer cohorts, IFNA22P RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of IFNA22P’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where IFNA22P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types IFNA22P is over-expressed in tumor, although a few such as LUSC show the opposite, repressed pattern.

HNSC, KIRC, and LUSC are the cancer types where IFNA22P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in IFNA22P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	IV	+0.095	.042	1	view →
KIRC	All	All	+0.047	.045	1	view →
LUSC	All	All	−0.041	.012	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: IFNA22P RNA expression & survival · all IFNA22P data types