Across TCGA patient cohorts, IFNA2 mutation is significantly associated with the total protein of many other genes, with 15 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible IFNA2-associated genes across cancer lineages are EGFR_pY1068, Notch1, and PCNA. Each is linked with IFNA2 in more than 1 cancer types. Because this analysis shows association rather than direction, both IFNA2-to-partner and partner-to-IFNA2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IFNA2→partner) and Y-score (partner→IFNA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	EGFR_pY1068 →	-0.241	-2.222	.023	.011	3	1
UCEC	Notch1 →	+0.194	+2.469	.001	.010	3	1
UCEC	PCNA →	+0.254	+2.222	.005	.011	3	1
UCEC	Annexin-1 →	+0.717	+2.341	.001	.019	3	1
UCEC	S6_pS240_S244 →	+0.391	+1.700	.023	.044	3	1
UCEC	STAT3_pY705 →	-0.392	-2.459	<.001	.018	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

Exploration

IFNA2 survival (RNA) · tumor vs normal (RNA) · all IFNA2 data types