Across TCGA patient cohorts, IFNA14 mutation is significantly associated with the immune_cell of many other genes, with 8 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible IFNA14-associated genes across cancer lineages are CD4+ T-cells, cDC, and DC. Each is linked with IFNA14 in more than 1 cancer types. Because this analysis shows association rather than direction, both IFNA14-to-partner and partner-to-IFNA14 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IFNA14→partner) and Y-score (partner→IFNA14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	CD4+ T-cells →	+0.004	+6.336	.023	.018	3	1
UCEC	cDC →	+0.071	+3.178	.046	.010	3	1
UCEC	DC →	+0.020	+2.688	.024	.009	3	1
UCEC	Erythrocytes →	+0.031	+2.393	.003	.017	3	1
UCEC	Hepatocytes →	+0.015	+1.747	.001	.041	3	1
UCEC	Mast cells →	+0.016	+2.850	.019	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

Exploration

IFNA14 survival (RNA) · tumor vs normal (RNA) · all IFNA14 data types